From the junction with the West Texas & Lubbock Railroad (former Santa Fe) trailing in from the southwest, the former Santa Fe line from Amarillo trailing in from the north, at Canyon Junction (MP 88.6/673.5), where single track, CTC, is replaced by Two Main Tracks, Track Warrant Control and mileposts are from Kansas City via Amarillo and Wellington, spurs from the southwest and northeast trailing in, the latter the rump of an erstwhile Crosbyton Railroad line, and the yard at Lubbock (MP 674.6), the line continues southeast, past East Lubbock (MP 676.6), where a spur from Goodpasture Grain and the Forth Worth & Denver station trails in from the west (and once continued across to the east), the 2MT, TWC, are replaced by single track, CTC, and the line speed remains 55 mph, the 4,916 ft. siding at Burris (MP 679.8), additional track at Sunray Grain Co. (MP 682.9), additional track at Great Plains Distributors (MP 682.4), additional track at Godbold Inc. (MP 683.5), and Posey.
There is a detector at MP 685.8, Slaton (MP 690.0), where an erstwhile line to Lamesa once left at a wye on the southwest side, the 9,497 ft. siding at Southland (MP 697.3), a turn south past the 5,400 ft. siding at Buenos (MP 703.6), where the speed limit is 45 mph, curvily south-southeast past a detector at MP 709.0, where the speed limit has returned to 55 mph, south past the 6,911 ft. siding at Post (MP 713.8), just south of due east and then southeast past the 5,482 ft. siding at Augustus (MP 720.3), south, east-southeast, and south-southeast past the 5,154 ft. siding at Justiceburg (MP 729.0), Cow Spur and a detector at MP 730.9, southeast and then south-southeast past the 7,543 ft. siding at Fullerville (MP 740.6), south and then southeast again past West Dermott (MP 746.4), Dermott, and East Dermott (MP 747.5).
The line turns south-southeast past a detector at MP 748.5, Brand, where the erstwhile Roscoe, Snyder & Pacific railway once came alongside to the west, southeast at the 5,701 ft. siding at Snyder (MP 756.9), past the place where the RS&P turned away, south-southeast past the 4,878 ft. siding at Hermleigh (MP 758.6), a detector at MP 770.8, and the 7,106 ft. siding at Pyron (MP 775.3), curvily east, south-southeast, and east-northeast past Bernecker, east-southeast past the 12,253 ft. siding at Gannon (MP 787.3), and southeast past a detector at MP 791.7, a mileage equation at MP 792.2=MP 461.0, the latter being miles from Galveston via Temple, Orient Junction (MP 460.7), where the erstwhile Kansas City, Mexico & Orient once trailed in from the north and the speed limit falls to 40 mph, a wye on the southwest side where the Texas & Oklahoma Railroad operates a rump of the erstwhile KCM&O line south to Maryneal, and Sweetwater (MP 459.6), where the speed limit rises to 45 mph.
The line turns east, past additional track at US Gypsum (MP 458.3), additional track at Georgia Pacific (MP 456.3), and the bridge carrying the former Texas & Pacific El Paso to Fort Worth line overhead, and then turns east-northeast to Tecific (MP 4454.5), where there is a connector on the north side used by BNSF trains heading between Clovis, NM, and Fort Worth on UP trackage rights while the line towards Brownwood and Temple continues ahead.